Biocompatible interaction of material with host tissue is the key to successful clinical application of biomaterial-based implant device. Our laboratory is working on the development of novel polymeric biomaterials as the carriers of cells and growth factors for engineering tissue regeneration. The polymers currently under study in our group include synthetic polymers (polylactides, polyglycolides, polyethyleneglycol and polypropylene oxides) and naturally derived biopolymers (collagen, hyaluronic acid, alginate, polygalacturonic acid and acemannan). We are interested in designing, isolating, synthesizing, modifying and characterizing these polymers of biomedical uses.
Our research interest focuses on three aspects: (1) to compose biohybrid polymeric materials aiming for engineering bone/cartilage repair and wound healing, (2) to unveil the underline molecular mechanisms of material/cell interaction by the approaches of nanotechnology and molecular imaging, (3) to develop biopolymers with pendent bioactive or reporting moieties using nanoparticles and bioconjugate chemistry. The final goal is to search and identify their specific clinical applications.
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